It's a different effect for each person I guess. I am in my 40s. I get regular hot flushes throughout the day. Hereditary I think. I eat reasonably healthy. 1st day I took one capsule in the morning. I wasn't expecting a miracle to bam it away. 2nd day still temperament hot flushes. 3rd day no change. Drinking plenty of bottled water. Feeling tired than normally would but flushes are still persistent. Stopped taking after the first week. 2 day break. Started again and still no change. As stated works differently for each person.